학술논문

Mesenchymal Stem Cells and Their Role in Neurodegenerative Diseases.
Document Type
Article
Source
Cells (2073-4409). May2024, Vol. 13 Issue 9, p779. 4p.
Subject
*MESENCHYMAL stem cells
*NEURODEGENERATION
*COMPACT bone
*ALZHEIMER'S disease
*CENTRAL nervous system diseases
*NEURAL stem cells
*DOPAMINE receptors
*SCRAPIE
*VAGUS nerve
Language
ISSN
2073-4409
Abstract
Mesenchymal stem cells (MSCs) have shown promise in the treatment of neurodegenerative diseases such as Alzheimer's, Parkinson's, and epilepsy. They have the ability to differentiate into different cell types and can modulate the inflammatory response, promote neuron survival, and release neurotrophic factors. Stem cells isolated from human dental pulp and exfoliated deciduous teeth are particularly promising for treating neurodegenerative conditions due to their easy extraction process and ability to develop into different types of mature neurons. The link between bone health and brain function is also highlighted, with the bidirectional communication between bones and nerves potentially offering new therapeutic strategies. Additionally, stem cells have been explored as a potential model for studying prion diseases, although further research is needed to determine their efficacy in treating these conditions. Overall, more research is needed to fully understand and apply the therapeutic potential of MSCs in neurodegenerative diseases. [Extracted from the article]