학술논문
Susceptibility to brain ischemia and the association between migraine and spontaneous cervical artery dissection.
Document Type
Article
Author
Del Zotto, Elisabetta; Grassi, Mario; Zedde, Marialuisa; Zini, Andrea; Bersano, Anna; Gandolfo, Carlo; Silvestrelli, Giorgio; Baracchini, Claudio; Cerrato, Paolo; Lodigiani, Corrado; Marcheselli, Simona; Paciaroni, Maurizio; Spalloni, Alessandra; Cappellari, Manuel; Del Sette, Massimo; Cavallini, Anna; Lotti, Enrico Maria; DeLodovici, Maria Luisa; Gentile, Mauro; Magoni, Mauro
Source
Subject
*MIGRAINE aura
*CEREBRAL ischemia
*MIGRAINE
*CAROTID artery dissections
*ISCHEMIC stroke
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Language
ISSN
0340-5354
Abstract
SCeAD affected predominantly a single artery (carotid, 870 patients [59.3%]; vertebral, 386 patients [26.3%]), whereas 212 patients (14.4%) had > 1 cervical artery involved. Dear Sirs, A recent hypothesis to explain the migraine-ischemic stroke (IS) association is that migraine might increase individual vulnerability to cerebral ischemia, making brain tissue more susceptible to ischemic injury [[1]]. Among migraine sufferers, we distinguished between "active migraine", which included participants with at least one self-reported migraine attack in the year preceding the baseline evaluation, and "prior (non-active) migraine", which included those who reported ever having had migraine but no attack in the year preceding the baseline evaluation. Actually, if the above is true, one would expect a higher prevalence of migraine and, possibly, migraine activity, among sCeAD patients who develop IS than among those who do not, as well as an association of migraine with sCeAD only or more prominent in the subgroup of patients with IS as disease manifestation compared to non-sCeAD subjects. [Extracted from the article]