학술논문

Embryonic Development of the Deer Mouse, Peromyscus maniculatus.
Document Type
Article
Source
PLoS ONE. 3/1/2016, Vol. 11 Issue 3, p1-15. 15p.
Subject
*EMBRYOLOGY
*PEROMYSCUS maniculatus
*BIOLOGICAL evolution
*GENETIC polymorphisms
*OPHTHALMOLOGY
Language
ISSN
1932-6203
Abstract
Deer mice, or Peromyscus maniculatus, are an emerging model system for use in biomedicine. P. maniculatus are similar in appearance to laboratory mice, Mus musculus, but are more closely related to hamsters than to Mus. The laboratory strains of Peromyscus have captured a high degree of the genetic variability observed in wild populations, and are more similar to the genetic variability observed in humans than are laboratory strains of Mus. The Peromyscus Genetic Stock Center at the University of South Carolina maintains several lines of Peromyscus harboring mutations that result in developmental defects. We present here a description of P. maniculatus development from gastrulation to late gestation to serve as a guide for researchers interested in pursuing developmental questions in Peromyscus. [ABSTRACT FROM AUTHOR]