학술논문
Cardiological assessment of first-degree relatives in sudden arrhythmic death syndrome.
Document Type
Journal Article
Author
Behr E; Wood DA; Wright M; Syrris P; Sheppard MN; Casey A; Davies MJ; McKenna W; Sudden Arrhythmic Death Syndrome (SADS) Steering Group (CORPORATE AUTHOR); Behr, E; Wood, D A; Wright, M; Syrris, P; Sheppard, M N; Casey, A; Davies, M J; McKenna, W; Sudden Arrhythmic Death Syndrome Steering Group (CORPORATE AUTHOR)
Source
Subject
Language
ISSN
0140-6736
Abstract
4.1% of sudden cardiac deaths in the 16-64 age-group are unexplained. In this group, cardiac pathological findings are normal and toxicological tests are negative; termed sudden arrhythmic death syndrome (SADS). We searched for evidence of inherited cardiac disease in cases of SADS. Of 147 first-degree relatives of 32 people who died of SADS, 109 (74%) underwent cardiological assessment. Seven (22%) of the 32 families were diagnosed with inherited cardiac disease: four with long QT syndrome; one with non-structural cardiac electrophysiological disease; one with myotonic dystrophy; and one with hypertrophic cardiomyopathy. Families of people who die of SADS should be offered assessment in centres with experience of inherited cardiac disease. [ABSTRACT FROM AUTHOR]