학술논문

The role of adenoviral vectors in genetic prodrug activation therapy in prostate cancer.
Document Type
Article
Source
Prostate Cancer & Prostatic Diseases. Dec2000Supplement, Vol. 3 Issue 1, pS10-S10. 1p.
Subject
*GENETIC vectors
*DRUG activation
*PROSTATE cancer
*CANCER cells
*DISEASE susceptibility
*GREEN fluorescent protein
*PROSTATE diseases
Language
ISSN
1365-7852
Abstract
The article discusses the role of adenoviral vectors in Genetic prodrug activation therapy (GPAT) in prostate cancer. Topics include GPAT is an innovative approach that can kill tumour cells by inserting suicide genes into cancer cells; and susceptibility of prostate cell lines to adenoviral transfection we have used an adenoviral vector containing green fluorescent protein (GFP) to transfect nine human prostate cell lines.