학술논문

Aspartic protease inhibitors.
Document Type
Article
Source
European Journal of Biochemistry. Mar2000 Part 2, Vol. 267 Issue 6, p1715. 8p.
Subject
*ASPARTIC proteinases -- Inhibitors
*VIRAL proteinases
*HIV
Language
ISSN
0014-2956
Abstract
Investigates the synthesis of human immunodeficiency virus-1 aspartic protease diaminodiol inhibitors. Inhibitory activity of peptide structure based on calculated enzyme-inhibitor complexation energies; Analysis of factors affecting inhibition efficiency; Correlations between inhibitor structure and binding activity.