학술논문
Clinical Features and Comparison of Kingella and Non-Kingella Endocarditis in Children, Israel.
Document Type
Journal Article
Author
Lowenthal, Alexander; Weisblum-Neuman, Hila; Birk, Einat; Ashkenazi-Hoffnung, Liat; Levy, Itzhak; Haim Ben-Zvi; Amir, Gabriel; Frenkel, Georgy; Bruckheimer, Elchanan; Yarden-Bilavsky, Havatzelet; Marom, Dafna; Shostak, Eran; Nahum, Elhanan; Dagan, Tamir; Chodick, Gabriel; Scheuerman, Oded; Ben-Zvi, Haim
Source
Subject
*ENDOCARDITIS
*INFECTIVE endocarditis
*CONGENITAL heart disease
*LYMPHOCYTE count
*DIAGNOSIS
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Language
ISSN
1080-6040
Abstract
Kingella spp. have emerged as an important cause of invasive pediatric diseases. Data on Kingella infective endocarditis (KIE) in children are scarce. We compared the clinical features of pediatric KIE cases with those of Streptococcus species IE (StIE) and Staphylococcus aureus IE (SaIE). A total of 60 patients were included in the study. Throughout the study period, a rise in incidence of KIE was noted. KIE patients were significantly younger than those with StIE and SaIE, were predominately boys, and had higher temperature at admission, history of oral aphthae before IE diagnosis, and higher lymphocyte count (p<0.05). Pediatric KIE exhibits unique features compared with StIE and SaIE. Therefore, in young healthy children <36 months of age, especially boys, with or without a congenital heart defect, with a recent history of oral aphthae, and experiencing signs and symptoms compatible with endocarditis, Kingella should be suspected as the causative pathogen. [ABSTRACT FROM AUTHOR]