학술논문

Normalization of hyperosmotic-induced inositol uptake by renal and endothelial cells is regulated...
Document Type
Article
Source
American Journal of Physiology. May2000 Part 1 of 2, Vol. 278 Issue 5, pC1011. 8p. 1 Chart, 13 Graphs.
Subject
*INOSITOL
*PHYSIOLOGICAL stress
*TRANSCRIPTION factors
*CELLS
Language
ISSN
0002-9513
Abstract
Demonstrates that removal of hyperosmotic stress causes an activation of the transcription factor NF-kappaB (NF-KB) in renal and endothelial cells. Myo-inositol functions in mammalian cells; Activation of NF-KB following postinduction normalization of hyperosmolarity; Effect of NF-KB activation on sodium-dependent myo-inositol cotransporter mRNA levels.