학술논문
A case of cutaneous lichen sclerosus et atrophicus effectively treated by extracorporeal photochemotherapy.
Document Type
Article
Author
Source
Subject
*LICHEN sclerosus et atrophicus
*PHOTOCHEMOTHERAPY
*INFLAMMATION
*LICHEN planus
*GRAFT versus host disease
*SCLERODERMA (Disease)
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Language
ISSN
0905-4383
Abstract
Lichen sclerosus et atrophicus ( LSA) is an inflammatory disease that affects the genitals, which was first described by Hallopeau in 1887 and is of unknown etiology. Only 15% of patients have an associated extra-genital form, and 2.5% have an isolated extra-genital form. LSA treatment remains poorly codified and mostly empirical. Here, we report a case of LSA, of mainly cutaneous form, which was effectively treated using extracorporeal photochemotherapy ( ECP). Remission was achieved quickly, after the fourth session, with excellent treatment tolerance. ECP is now recognized as an effective treatment for erosive lichen planus, graft-versus-host disease (GVHD), and scleroderma. Thus, we began ECP treatment for our cases of LSA based on clinical and/or anatomopathological similarities between LSA and these commonly ECP-treated disorders. The fact that ECP is effective in LSA, GV HD, erosive lichen planus, and scleroderma strengthen the hypothesis that there is a common link between these four conditions. [ABSTRACT FROM AUTHOR]