학술논문
Fibrinogen response with simvastatin versus atorvastatin in familial hypercholesterolemia.
Document Type
Journal Article
Author
Source
Subject
*FIBRINOGEN
*STATINS (Cardiovascular agents)
*HYPERCHOLESTEREMIA
*
*
Language
ISSN
0002-9149
Abstract
The clinical and biochemical determinants of the fibrinogen response to simvastatin or atorvastatin therapy were assessed in 130 patients with severe polygenic or familial hypercholesterolemia treated in a randomized open-trial format design. Hyperfibrinogenemia was associated with atorvastatin, baseline fibrinogen, and initial concentration and change in concentration of apolipoprotein B or low-density lipoprotein cholesterol. [ABSTRACT FROM AUTHOR]