학술논문
Oncogenic Brain Metazoan Parasite Infection.
Document Type
Article
Author
Source
Subject
*PARASITIC diseases
*ONCOGENES
*NEUROCYSTICERCOSIS
*GLIOMAS
*HEMATOLOGIC malignancies
*CANCER in women
*IMMUNOHISTOCHEMISTRY
*CYTOPLASMIC filaments
*DISEASE risk factors
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Language
ISSN
2090-6668
Abstract
Multiple observations suggest that certain parasitic infections can be oncogenic. Among these, neurocysticercosis is associated with increased risk for gliomas and hematologic malignancies. We report the case of a 71-year-old woman with colocalization of a metazoan parasite, possibly cysticercosis, and a WHO grade IV neuroepithelial tumor with exclusively neuronal differentiation by immunohistochemical stains (immunopositive for synaptophysin, neurofilament protein, and Neu-N and not for GFAP, vimentin, or S100). The colocalization and temporal relationship of these two entities suggest a causal relationship. [ABSTRACT FROM AUTHOR]