학술논문
Gold-catalysed cross-coupling between aryldiazonium salts and arylboronic acids: probing the usefulness of photoredox conditions.
Document Type
Article
Source
Subject
*SALTS
*GOLD catalysts
*COUPLING reactions (Chemistry)
*BORONIC acids
*ARYL group
*
*
*
*
Language
ISSN
1359-7345
Abstract
The synthesis of biaryl compounds from aryldiazonium salts and arylboronic acids was achieved using PPh3AuCl as catalyst, CsF as base and acetonitrile as solvent. Combined to photosensitizers, irradiation by blue LEDs allowed accelerating the reaction and expanding its scope. Various functional groups were compatible including bromoaryls, iodoaryls, aldehydes and alcohols. A 2-iodobenzyl alcohol moiety was smoothly introduced by this method, enabling its consecutive isotopic labelling by a Pd-catalysed alkoxycarbonylation. [ABSTRACT FROM AUTHOR]