학술논문
General Last-Step Labeling of Biomolecule-Based Substratesby [12C], [13C], and [11C] CarbonMonoxide.
Document Type
Article
Source
Subject
*CARBON monoxide
*CARBON isotopes
*BIOMOLECULES
*BIOCHEMICAL substrates
*BIOCONJUGATES
*LIGANDS (Biochemistry)
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Language
ISSN
1523-7060
Abstract
Alkaloid-, steroid-,biotin-, carbohydrate-, nucleoside-, and peptide-basedbioconjugates are easily labeled with CO by a last-step palladium-catalyzedcarbonylation. The choice of the [12C], [13C],or [11C] isotope opens the way to a new class of potentialtracers or ligands easily available for various applications. [ABSTRACT FROM AUTHOR]