학술논문

Executive Response Monitoring and Inhibitory Control in Children With Phenylketonuria: Effects of Expectancy.
Document Type
Article
Source
Developmental Neuropsychology. 2013, Vol. 38 Issue 3, p139-152. 14p. 1 Chart, 3 Graphs.
Subject
*PHENYLKETONURIA
*GENETIC disorders in children
*EXECUTIVE ability in children
*PHENYLALANINE
*HEALTH expectancy
*REACTION time
*PATIENTS
Language
ISSN
8756-5641
Abstract
Response monitoring (post-error slowing) and inhibitory control (commission errors) were examined in children with phenylketonuria (PKU) and controls (6–18 years) using Go/No-Go tasks with higher (PKUn = 37; controln = 55) versus lower (PKUn = 24; controln = 25) non-target expectancy. On both tasks children with PKU exhibited impaired monitoring and inhibitory control, but the post-error slowing pattern was different. With higher expectancy children with PKU slowed more (less efficient monitoring) and with lower expectancy slowed less (less monitoring) than controls. No effects of age or phenylalanine level were noted. These results indicate that expectancy differentially effects monitoring and inhibitory control in PKU. [ABSTRACT FROM AUTHOR]