학술논문
Follicle Structure Influences the Availability of Oxygen to the Oocyte in Antral Follicles.
Document Type
Article
Author
Source
Subject
*PREDICTION models
*OVARIAN atresia
*BODY fluids
*MATHEMATICAL models
*OXYGEN in the body
*
*
*
*
Language
ISSN
1748-670X
Abstract
The ability of an oocyte to successfully mature is highly dependent on intrafollicular conditions, including the size and structure of the follicle. Here we present a mathematical model of oxygen transport in the antral follicle. We relate mean oxygen concentration in follicular fluid of bovine follicles to the concentration in the immediate vicinity of the cumulus-oocyte complex (COC). The model predicts that the oxygen levels within the antral follicle are dependent on the size and structure of the follicle and that the mean level of dissolved oxygen in follicular fluid does not necessarily correspond to that reaching the COC. [ABSTRACT FROM AUTHOR]