부산대학교 도서관

Ultrasound is an established modality for quantification of vascular function in clinical studies of cardiovascular disease. We determined whether cardiovascular magnetic resonance imaging (CMR) can provide a comparable assessment of vascular function. In seventeen control subjects, we used CMR to quantify endothelium-dependent (flow mediated dilatation, FMD) and endothelium-independent dilatation of the brachial artery, brachial and carotid distensibility, aortic compliance, and pulse wave velocity. These were compared to brachial and carotid measurements obtained by established ultrasound protocols. Twelve of the volunteers then underwent repeated measurements with both modalities. There was good agreement between imaging modalities for measures of endothelial function and arterial structure in the same subjects (difference between CMR and ultrasound for FMD = 0.14 ± 6.8%, and brachial artery area = - 0.7 ± 2.2 mm 2 , correlation between modalities for FMD = 0.62, p = 0.01 and for area = 0.87, p = one-stop integrated assessment of both peripheral and central measures of vascular function. [ABSTRACT FROM AUTHOR]