학술논문
Current Strategies on the Enantioselective Synthesis of Modified Nucleosides.
Document Type
Article
Source
Subject
*NUCLEOSIDE synthesis
*AMINATION
*NUCLEOSIDE derivatives
*ALLYL alcohol
*CHEMICAL reactions
*WITTIG reaction
*PYRIMIDINE nucleosides
*SILYL group
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Language
ISSN
0936-5214
Abstract
This article provides an overview of the current strategies for the enantioselective synthesis of modified nucleosides, which have been used in the treatment of various diseases, including viruses. The focus is on the modifications that can be made to different parts of the nucleoside structure to create therapeutically useful compounds. The article discusses the latest developments in the synthesis of cyclic and acyclic nucleosides, highlighting various methods and reactions that can be used to achieve high yields and enantioselectivities. The authors also acknowledge the institutions that supported their research. [Extracted from the article]