부산대학교 도서관

The article discusses the use of genomics to understand severe cases of COVID-19. It highlights the devastating effects of the pandemic and the inequalities in health and social care provision that it has exposed. The article emphasizes the power of international scientific collaborations in characterizing the epidemiology and pathogenesis of the disease, developing testing and treatment strategies, and producing an effective vaccine. It discusses the findings of various genome-wide association studies (GWAS) that have identified genomic loci associated with severe COVID-19 illness, including genes involved in antiviral immunity and lung inflammation. The article also explores the potential for these genomic associations to inform the development of targeted therapies for COVID-19. It acknowledges the limitations of the studies, such as the lack of granular phenotypic data and the underrepresentation of non-European populations, and emphasizes the need for more inclusive and diverse genomic studies. Overall, the article highlights the importance of collaborative and unbiased genomics research in understanding and combating severe cases of COVID-19. [Extracted from the article]