학술논문
Similar Prevalence of Plasmodium falciparum and Non--P. falciparum Malaria Infections among Schoolchildren, Tanzania.
Document Type
Article
Author
Sendor, Rachel; Mitchell, Cedar L.; Chacky, Frank; Mohamed, Ally; Mhamilawa, Lwidiko E.; Molteni, Fabrizio; Nyinondi, Ssanyu; Kabula, Bilali; Mkali, Humphrey; Reaves, Erik J.; Serbantez, Naomi; Kitojo, Chonge; Makene, Twilumba; Kyaw, Thwai; Muller, Meredith; Mwanza, Alexis; Eckert, Erin L.; Parr, Jonathan B.; Lin, Jessica T.; Juliano, Jonathan J.
Source
Subject
Language
ISSN
1080-6040
Abstract
Achieving malaria elimination requires considering both Plasmodium falciparum and non--P. falciparum infections. We determined prevalence and geographic distribution of 4 Plasmodium spp. by performing PCR on dried blood spots collected within 8 regions of Tanzania during 2017. Among 3,456 schoolchildren, 22% had P. falciparum, 24% had P. ovale spp., 4% had P. malariae, and 0.3% had P. vivax infections. Most (91%) schoolchildren with P. ovale infections had low parasite densities; 64% of P. ovale infections were single-species infections, and 35% of those were detected in low malaria endemic regions. P. malariae infections were predominantly (73%) co-infections with P. falciparum. P. vivax was detected mostly in northern and eastern regions. Co-infections with >1 non--P. falciparum species occurred in 43% of P. falciparum infections. A high prevalence of P. ovale infections exists among schoolchildren in Tanzania, underscoring the need for detection and treatment strategies that target non--P. falciparum species. [ABSTRACT FROM AUTHOR]