학술논문
Eculizumab for a catastrophic relapse in NMOSD: case report.
Document Type
Article
Author
Source
Subject
*NEUROMYELITIS optica
*CENTRAL nervous system
*ECULIZUMAB
*SPINAL cord
*OPTIC nerve
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*
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Language
ISSN
1590-1874
Abstract
Neuromyelitis optica spectrum disorders (NMOSD) are a group of inflammatory disorders of central nervous system characterized by immune-mediated demyelination and axonal damage, predominantly affecting spinal cord and optic nerves. This case report describes a 47-year-old woman with an aggressive form of seropositive NMOSD who had previously been treated with corticosteroids, plasma exchange, and cyclophosphamide. She experienced a life-threatening relapse that did not respond to conventional treatment, but ultimately showed a positive response to eculizumab. Furthermore, we describe the role of sNfL. [ABSTRACT FROM AUTHOR]