학술논문
ALSUntangled #75: Portable neuromodulation stimulator therapy.
Document Type
Article
Author
Officer, Laurel; Armon, Carmel; Barkhaus, Paul; Beauchamp, Morgan; Benatar, Michael; Bertorini, Tulio; Bowser, Robert; Bromberg, Mark; Brown, Andrew; Carbunar, Olimpia Mihaela; Carter, Gregory T.; Crayle, Jesse; Denson, Keelie; Feldman, Eva; Fullam, Timothy; Heiman-Patterson, Terry; Jackson, Carlayne; Jhooty, Sartaj; Levinson, Danelle; Li, Xiaoyan
Source
Subject
*NEUROMODULATION
*AMYOTROPHIC lateral sclerosis
*BRAIN injuries
*FACIAL nerve
*TRIGEMINAL nerve
*
*
*
*
Language
ISSN
2167-8421
Abstract
Spurred by patient interest, ALSUntangled herein examines the potential of the Portable Neuromodulation Stimulator (PoNS™) in treating amyotrophic lateral sclerosis (ALS). The PoNS™ device, FDA-approved for the treatment of gait deficits in adult patients with multiple sclerosis, utilizes translingual neurostimulation to stimulate trigeminal and facial nerves via the tongue, aiming to induce neuroplastic changes. While there are early, promising data for PoNS treatment to improve gait and balance in multiple sclerosis, stroke, and traumatic brain injury, no pre-clinical or clinical studies have been performed in ALS. Although reasonably safe, high costs and prescription requirements will limit PoNS accessibility. At this time, due to the lack of ALS-relevant data, we cannot endorse the use of PoNS as an ALS treatment. [ABSTRACT FROM AUTHOR]