학술논문
ALSUntangled #70: caffeine.
Document Type
Article
Author
Hatch, Jessica; Barkhaus, Paul; Barnes, Benjamin; Beauchamp, Morgan; Benatar, Michael; Bertorini, Tulio; Bowser, Robert; Bromberg, Mark; Brown, Andrew; Mascias Cadavid, Javier; Carter, Gregory T.; Cole, Nicholas; Crayle, Jesse; Dimachkie, Mazen; Ennist, David; Feldman, Eva; Fullam, Timothy; Heiman-Patterson, Terry; Jhooty, Sartaj; Levine, Todd
Source
Subject
*AMYOTROPHIC lateral sclerosis
*CAFFEINE
*
Language
ISSN
2167-8421
Abstract
ALSUntangled reviews alternative and off-label treatments for people living with amyotrophic lateral sclerosis (PALS). Here, we review caffeine which has plausible mechanisms for slowing ALS progression. However, pre-clinical studies are contradictory, and a large case series showed no relationship between caffeine intake and ALS progression rate. While low doses of caffeine are safe and inexpensive, higher doses can cause serious side effects. At this time, we cannot endorse caffeine as a treatment to slow ALS progression. [ABSTRACT FROM AUTHOR]