학술논문
Impact of diabetes status on immunogenicity of trivalent inactivated influenza vaccine in older adults.
Document Type
Article
Author
Spencer, Sarah; Chung, Jessie R.; Belongia, Edward A.; Sundaram, Maria; Meece, Jennifer; Coleman, Laura A.; Zimmerman, Richard K.; Nowalk, Mary Patricia; Moehling Geffel, Krissy; Ross, Ted; Carter, Chalise E.; Shay, David; Levine, Min; Liepkalns, Justine; Kim, Jin Hyang; Sambhara, Suryaprakash; Thompson, Mark G.; Flannery, Brendan
Source
Subject
*INFLUENZA
*OLDER people
*TYPE 2 diabetes
*INFLUENZA vaccines
*IMMUNE response
*FLU vaccine efficacy
*CINNAMON
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Language
ISSN
1750-2640
Abstract
Individuals with type 2 diabetes mellitus experience high rates of influenza virus infection and complications. We compared the magnitude and duration of serologic response to trivalent influenza vaccine in adults aged 50–80 with and without type 2 diabetes mellitus. Serologic response to influenza vaccination was similar in both groups: greater fold‐increases in antibody titer occurred among participants with lower pre‐vaccination antibody titers. Waning of antibody titers was not influenced by diabetes status. [ABSTRACT FROM AUTHOR]