학술논문
Voxel-wise magnetization transfer imaging study of effects of natalizumab and IFNβ-1a in multiple sclerosis.
Document Type
Article
Author
Source
Subject
*DRUG side effects
*NATALIZUMAB
*INTERFERON beta-1a
*MULTIPLE sclerosis treatment
*MYELINATION
*DEMYELINATION
*MAGNETIC resonance imaging
*QUANTITATIVE research
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Language
ISSN
1352-4585
Abstract
The article presents a study which examines the impact of natalizumab monotherapy and interferon beta-1a (IFNβ-1a) in patients with multiple sclerosis (MS). The study uses magnetic resonance imaging (MRI) and statistical analysis to determine the effect of natalizumab and IFNβ-1a in multiple sclerosis. Results show that natalizumab can promote remyelination and stabilize demyelination in lesions and normal appearing brain tissue (NABT).