학술논문
Spontaneous Remission of B-Cell Chronic Lymphocytic Leukemia Associated With T Lymphocytic Hyperplasia in Bone Marrow.
Document Type
Article
Source
Subject
*B cells
*LYMPHOCYTIC leukemia
*T cells
*HYPERPLASIA
*BONE marrow
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Language
ISSN
0038-4348
Abstract
ABSTRACT: Spontaneous remissions in B-cell chronic lymphocytic leukemia (B-CLL) are rare and none of them has been studied with immunophenotyping (by flow cytometry and immunohistochemistry) and genotyping. In this patient, studied after spontaneous remission had occurred, there was a residual T-lymphocytic hyperplasia in the bone marrow with a normal CD4:CD8 ratio. Absolute CD4 and CD8 counts and CD4:CD8 ratio in the peripheral blood were normal. Flow cytometry revealed no B-CLL cells in the peripheral blood and less than 2% B-CLL cells in the bone marrow. [ABSTRACT FROM AUTHOR]