학술논문
Human Papillomavirus Status in Sinonasal Adenoid Cystic Carcinoma.
Document Type
Article
Author
Source
Subject
*ADENOID cystic carcinoma
*HUMAN papillomavirus
*PARANASAL sinuses
*PAPILLOMAVIRUSES
*FLUORESCENCE in situ hybridization
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Language
ISSN
2193-6331
Abstract
This article, published in the Journal of Neurological Surgery, explores the relationship between human papillomavirus (HPV) and sinonasal adenoid cystic carcinoma (AdCC). The study analyzed fifteen specimens from patients with AdCC and found that while all the tumors were p16 patchy positive, they were HPV negative for the subtypes tested. The results suggest that there is no correlation between the HPV subtypes tested and AdCC, but indicate that p16 may be dysregulated in AdCC. Further investigation into the role of p16 in sinonasal AdCC is warranted. [Extracted from the article]