학술논문
Psychotropic medication use in anorexia nervosa between 1997 and 2009.
Document Type
Article
Author
Source
Subject
*ANTIPSYCHOTIC agents
*SEROTONIN uptake inhibitors
*ANOREXIA nervosa
*ANTHROPOMETRY
*COMPARATIVE studies
*FISHER exact test
*LONGITUDINAL method
*HEALTH outcome assessment
*RESEARCH funding
*STATISTICS
*T-test (Statistics)
*DATA analysis
*BONE density
*BODY mass index
*TREATMENT effectiveness
*DESCRIPTIVE statistics
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Language
ISSN
0276-3478
Abstract
Objective: Despite a lack of data demonstrating benefit, psychotropic medications are frequently prescribed for patients with anorexia nervosa. Method: We studied 525 women (18-54 years of age) with anorexia nervosa who presented to the Clinical Research Center at the Massachusetts General Hospital between January 1997 and December 2009. For this analysis, participants were a priori divided into two groups based on date of presentation (Group I: participants presenting between 1997 and 2002; Group II: participants presenting between 2003 and 2009). Results: Overall, 53% of participants reported current use of any psychotropic medication; 48.4% reported use of an antidepressant and 13% reported use of an antipsychotic. Twice as many participants in Group II (18.5%) reported using atypical antipsychotics as compared to Group I (8.9%) ( p = 0.002). Discussion: A majority of participants with anorexia nervosa report using psychotropic medications despite lack of data supporting their efficacy. These data are concerning given the known adverse effects of these medications. © 2012 by Wiley Periodicals, Inc. (Int J Eat Disord 2012) [ABSTRACT FROM AUTHOR]