학술논문
Generalized verrucosis in GATA2 deficiency successfully treated with systemic acitretin and trichloroacetic acid.
Document Type
Article
Source
Subject
*TREATMENT effectiveness
*SYMPTOMS
*PAPILLOMAVIRUS diseases
*BONE marrow
*IMMUNOLOGICAL deficiency syndromes
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Language
ISSN
0736-8046
Abstract
Generalized verrucosis is a clinical manifestation of human papillomavirus infection. Patients with generalized verrucosis present with over 20 verrucae distributed over various anatomical sites. The disorder occurs in association with several genetic syndromes with immunodeficiency, including GATA2 deficiency. We report a 12‐year‐old boy with GATA2 deficiency and generalized verrucosis that worsened after cyclosporine use following bone marrow transplant. Systemic treatment with acitretin and topical application of trichloroacetic acid, likely along with immune reconstitution, led to complete remission. [ABSTRACT FROM AUTHOR]