학술논문
Proposal for Human Respiratory Syncytial Virus Nomenclature below the Species Level.
Document Type
Journal Article
Author
Salimi, Vahid; Viegas, Mariana; Trento, Alfonsina; Agoti, Charles N.; Anderson, Larry J.; Avadhanula, Vasanthi; Bahl, Justin; Bont, Louis; Brister, J. Rodney; Cane, Patricia A.; Galiano, Mónica; Graham, Barney S.; Hatcher, Eneida L.; Hellferscee, Orienka; Henke, David M.; Hirve, Siddhivinayak; Jackson, Sandra; Keyaerts, Els; Kragten-Tabatabaie, Leyla; Lindstrom, Stephen
Source
Subject
*RESPIRATORY syncytial virus
*RESEARCH
*BIOLOGICAL evolution
*GENETICS
*RESEARCH methodology
*MEDICAL cooperation
*EVALUATION research
*COMPARATIVE studies
*GENOTYPES
*RESPIRATORY syncytial virus infections
*MOLECULAR epidemiology
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Language
ISSN
1080-6040
Abstract
Human respiratory syncytial virus (HRSV) is the leading viral cause of serious pediatric respiratory disease, and lifelong reinfections are common. Its 2 major subgroups, A and B, exhibit some antigenic variability, enabling HRSV to circulate annually. Globally, research has increased the number of HRSV genomic sequences available. To ensure accurate molecular epidemiology analyses, we propose a uniform nomenclature for HRSV-positive samples and isolates, and HRSV sequences, namely: HRSV/subgroup identifier/geographic identifier/unique sequence identifier/year of sampling. We also propose a template for submitting associated metadata. Universal nomenclature would help researchers retrieve and analyze sequence data to better understand the evolution of this virus. [ABSTRACT FROM AUTHOR]