학술논문
Rapid remineralization of multiple disseminated bone lesions after high-dose cytarabine in a patient with isolated myeloid sarcoma.
Document Type
Article
Author
Source
Subject
*DRUG side effects
*CYTARABINE
*ACUTE myeloid leukemia
*SARCOMA
*BONE injuries
*DRUG dosage
*PROGNOSIS
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Language
ISSN
0902-4441
Abstract
Isolated myeloid sarcoma is a rare presentation of acute myeloid leukemia. There are limited data available concerning the prognostic relevance and the right treatment strategy for this clinical scenario. Here, we report a case of acute myeloid leukemia with extensive lesions and fractures in multiple bones in a 64-yr-old male patient. Remarkably, treatment with a high-dose cytarabine regimen led to rapid remineralization of all bone lesions and recovery of the patient's mobility within a few weeks. Thereby, surgical treatment and radiotherapy could be avoided, supporting the role of intensive induction and standard consolidation chemotherapy as first-line treatment for myeloid sarcoma. [ABSTRACT FROM AUTHOR]