부산대학교 도서관

Background: Tangential vitreo-foveal traction resulting in full-thickness macular hole is an important cause of visual loss. Purpose: To determine, correlate and evaluate the factors that affect the anatomical and visual outcome of macular hole surgery. Method: Retrospective analysis of all cases of macular hole surgery undertaken by a single surgeon (RDB) between 1995 and 1998. Results: One hundred eyes were analysed with a minimum follow-up of 3 months. One operation anatomical success rate was 95%. Anatomically successful eyes had visual acuity improvement of one or more lines in 73.4% and two or more lines in 66.3%. Failure to remove diaphanous contractile ‘epiretinal’ membranes (presumably the internal limiting membrane) around the macular hole was significantly associated with anatomical failure (P < 0.001). Improvement of two or more lines of visual acuity was significantly associated with successful anatomical closure of the macular hole (P = 0.001). The success rate was highest in the more recent cases, suggesting a learning curve effect. Postoperatively, cataract developed or progressed in 96% of phakic eyes. Retinal detachment occurred in 6%, with all eyes having the retina reattached following subsequent surgery. Gross retinal pigment epithelial changes at the macula region developed in 3%. Conclusion: Meticulous rapid dissection of adherent, diaphanous ‘epiretinal’ membrane around the macular hole, combined with gas tamponade and postoperative posturing, result in successful anatomical closure with improved visual acuity. [ABSTRACT FROM AUTHOR]