학술논문
Q Fever Risk in Patients Treated with Chronic Antitumor Necrosis Factor-Alpha Therapy.
Document Type
Article
Author
Source
Subject
*ANTINEOPLASTIC agents
*Q fever
*TUMOR necrosis factors
*GRAM-negative bacteria
*PATIENTS
*DIAGNOSIS
*THERAPEUTICS
*
*
*
*
*
*
Language
ISSN
2090-6625
Abstract
Q fever is a zoonotic bacterial disease caused by Coxiella burnetii. Tumor necrosis factor-alpha (TNF-α) plays a pivotal role in the defense against infection with this Gram-negative coccobacillus. Theoretically, patients who are treated with anti-TNF-α medications are at risk for developing chronic Q fever. We present two patients who developed Q fever while being treated with anti-TNF-α agents and discuss the significance of timely diagnosis of C. burnetii infection in these patients. [ABSTRACT FROM AUTHOR]