학술논문

One-Pot Three-Component Synthesis of Bispyrazole-thiazolepyran-2-one Heterocyclic Hybrids.
Document Type
Article
Source
Synlett. 2018, Vol. 29 Issue 13, p1776-1781. 6p.
Subject
*PYRAZOLES
*HETEROCYCLIC chemistry
*THIAZOLES
Language
ISSN
0936-5214
Abstract
A new series of some interesting bispyrazole-thiazole-pyran-2-one heterocyclic hybrids has been efficiently synthesized via a onepot catalyst-free three-component reaction of a-bromoacetylated pyran-2-one derivatives, thiosemicarbazide, and polysubstituted-1-(1Hpyrazol-4-yl)butane-1,3-diones. This multicomponent procedure has been advantageously applied to prepare a structural diversity of heterocyclic hybrids characterized by extensive 1D and 2D NMR spectroscopic studies. [ABSTRACT FROM AUTHOR]