학술논문
The Many Flavors of Model-Based Meta-Analysis: Part I-Introduction and Landmark Data.
Document Type
Article
Author
Source
Subject
*DRUG development
*PHARMACEUTICAL industry
*BENCHMARKING (Management)
*BAYESIAN analysis
*META-analysis
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Language
ISSN
2163-8306
Abstract
Meta-analysis is an increasingly important aspect of drug development as companies look to benchmark their own compounds with the competition. There is scope to carry out a wide range of analyses addressing key research questions from preclinical through to postregistration. This set of tutorials will take the reader through key model-based meta-analysis (MBMA) methods with this first installment providing a general introduction before concentrating on classical and Bayesian methods for landmark data. [ABSTRACT FROM AUTHOR]