학술논문
A 16‐month‐long experience of COVID‐19 in allogeneic haematopoietic stem cell transplantation recipients: An SFGM‐TC multicentre cohort study.
Document Type
Article
Author
Xhaard, Aliénor; Xhaard, Constance; Rubio, Marie‐Therese; Berceanu, Ana; Botella‐Garcia, Carmen; Coman, Tereza; Tavernier, Emmanuelle; Labussière‐Wallet, Hélène; Chevallier, Patrice; Legrand, Faezeh; Thiebaut, Anne; Menard, Anne‐Lise; Paillard, Catherine; Chantepie, Sylvain; Robin, Marie; Nguyen, Stephanie
Source
Subject
*HEMATOPOIETIC stem cell transplantation
*RESPIRATORY diseases
*COVID-19
*COHORT analysis
MORTALITY risk factors
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Language
ISSN
0007-1048
Abstract
Summary: This 16‐month‐long multicentre retrospective study of 225 allogeneic haematopoietic stem cell transplantation (alloHSCT) recipients with COVID‐19 examines risk factors for severity and mortality, describing the successive waves of infections (from March to June 2020 and from August 2020 to June 2021). We confirm the negative role of low respiratory tract disease and immunosuppressive treatment. We highlight significantly lower percentages of severe forms and COVID‐19‐related mortality during the second wave. Monthly comparative evolution of cases in alloHSCT recipients and in the French population shows a higher number of cases in alloHSCT recipients during the first wave and a decrease from February 2021. [ABSTRACT FROM AUTHOR]