부산대학교 도서관

Presents the results of a study focused on clones producing antibodies of more than one class. Demonstration that clones producing antibodies directed against oligo-D-alanine (D-ala) determinants in X-irradiated recipient mice after transfer of limited numbers of spleen and thymus cells; Comparison of IgM and IgG1 combining sites by affinity and specificity measurements; Conclusion that a single precursor cell can give rise to a clone producing antibodies of the IgM class and different IgG subclasses all of which share combining sites.