학술논문

Putative candidate genes for canine hypoadrenocorticism (Addison's disease) in multiple dog breeds.
Document Type
Article
Source
Veterinary Record: Journal of the British Veterinary Association. 11/1/2014, Vol. 175 Issue 17, preceding p430-430. 5p. 2 Charts.
Subject
*ADDISON'S disease
*SINGLE nucleotide polymorphisms
*AUTOIMMUNE diseases
*ADRENAL diseases
*ALLELES
Language
ISSN
0042-4900
Abstract
The article presents a study which aims to identify whether genes that have been associated with human Addison's disease related with canine Addison's disease. It mentions that the study uses 42 putatively associated single nucleotide polymorphisms from 17 genes in five breeds and one gene showed a putative allelic relationship in two different breeds. It is inferred that deciphering the risk alleles will need an additional multibreed genetic analyses of affected and un-affected dogs.