학술논문
Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments.
Document Type
Article
Author
Source
Subject
*AFFECTIVE disorders
*GABA
*AMANTADINE
*
*
Language
ISSN
1359-4184
Abstract
Discusses the role of glutamate and γ-amino butyric acid (GABA) systems in the pathophysiology and treatment of mood disorders. Antimanic effects of drugs that reduce glutamatergic activity or glutamate receptor-related signal transduction; Evidence of N-methyl-D-aspartate receptor antagonist antidepressant activity in animal models; Antidepressant efficacy of amantadine.