학술논문
Vitamin D in the General Population of Young Adults with Autism in the Faroe Islands.
Document Type
Article
Author
Source
Subject
*AUTISM
*BLOOD testing
*BLOOD collection
*SIBLINGS
*CHI-squared test
*CONFIDENCE intervals
*STATISTICAL correlation
*INTERVIEWING
*LONGITUDINAL method
*PARENTS
*POPULATION research
*QUESTIONNAIRES
*RESEARCH funding
*STATISTICS
*T-test (Statistics)
*VITAMIN D deficiency
*WECHSLER Adult Intelligence Scale
*LOGISTIC regression analysis
*DATA analysis
*DEMOGRAPHIC characteristics
*CROSS-sectional method
*CASE-control method
*DATA analysis software
*ODDS ratio
*MANN Whitney U Test
DIETETICS research
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Language
ISSN
0162-3257
Abstract
Vitamin D deficiency has been proposed as a possible risk factor for developing autism spectrum disorder (ASD). 25-Hydroxyvitamin D (25(OH)D) levels were examined in a cross-sectional population-based study in the Faroe Islands. The case group consisting of a total population cohort of 40 individuals with ASD (aged 15-24 years) had significantly lower 25(OH)D than their 62 typically-developing siblings and their 77 parents, and also significantly lower than 40 healthy age and gender matched comparisons. There was a trend for males having lower 25(OH)D than females. Effects of age, month/season of birth, IQ, various subcategories of ASD and Autism Diagnostic Observation Schedule score were also investigated, however, no association was found. The very low 25(OH)D in the ASD group suggests some underlying pathogenic mechanism. [ABSTRACT FROM AUTHOR]