학술논문
The variance in phosphorylated, insoluble ⍺-synuclein in humans, rats, and mice is not mainly driven by biological sex.
Document Type
Article
Author
Source
Subject
*ALPHA-synuclein
*SEX (Biology)
*FATTY acid-binding proteins
*OLFACTORY cortex
*MICE
*AMYGDALOID body
*LEWY body dementia
*ENTORHINAL cortex
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Language
ISSN
0001-6322
Abstract
For example, the OB and olfactory peduncle may be affected with Lewy pathology in early stages of dementia with Lewy bodies (DLB) and Parkinson's disease (PD), particularly in cases with amygdalar predominance [[1], [5]]. Keywords: Synuclein; Sex; Lewy body; Preformed fibril; Parkinson's disease EN Synuclein Sex Lewy body Preformed fibril Parkinson's disease 651 654 4 09/15/23 20231001 NES 231001 K. As all lifeforms must display sensitivity to surrounding chemicals, the mammalian olfactory bulb (OB) and its peripheral fibers have evolved to sample the air. Previously, we noted denser inclusions in some limbic structures of female mice after OB/AON fibril infusions [[10]], but AI-driven analyses reveal that female mice form larger limbic inclusions than do males [[4]]. [Extracted from the article]