학술논문

Editorial for the Special Issue "Genetics and Genomics of Gastrointestinal Cancers: From Prevention to Treatment".
Document Type
Editorial
Source
Genes. Sep2023, Vol. 14 Issue 9, p1821. 4p.
Subject
*GENETICS
*GASTROINTESTINAL cancer
*CANCER prevention
*NUTRITIONAL genomics
*PROGRAMMED cell death 1 receptors
*GENOMICS
*IMMUNE checkpoint proteins
Language
ISSN
2073-4425
Abstract
They identified three pathogenic variants in two diffuse GC cases: a pathogenic variant in the I CDH1 i gene in one patient and two pathogenic variants in the I VEGFA i and I FANCA i genes in a second patient. According to the latest estimate from GLOBOCAN 2020, approximately 18.1 million new cancer cases were diagnosed in 2020 around the world [[1]]. Gastrointestinal (GI) cancers are in the top five, accounting for 26% of the global cancer incidence and 35% of all cancer-related deaths [[2]]. Calvello et al. [[9]] compared the genetic testing approach (single-gene vs. multi-gene panel testing) in a retrospective cohort of 54 gastric cancer (GC) patients. [Extracted from the article]