학술논문

P53 Gene Mutation in a T-Acute Lymphoblastic Leukemia Cell Line (Loucy) with t(16:20) and....
Document Type
Article
Source
Leukemia & Lymphoma. May98, Vol. 29 Issue 5/6, p607. 5p. 2 Diagrams.
Subject
*LYMPHOBLASTIC leukemia
*T cells
*CELL lines
Language
ISSN
1042-8194
Abstract
Describes p53 mutation in a human T-acute lymphoblastic leukemia cell line (Loucy) with t(16:20) and 5q- chromosomal aberrations. Identification of a point mutation at codon 272 of the p53 gene; Molecular mechanisms underlying the alterations; Cytogenetic changes of the cell line.