학술논문
Rustrela Virus as Putative Cause of Nonsuppurative Meningoencephalitis in Lions.
Document Type
Article
Author
Source
Subject
*MENINGOENCEPHALITIS
*PURKINJE cells
*LIONS
*IN situ hybridization
*ASTROCYTES
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*
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*
Language
ISSN
1080-6040
Abstract
Retrospective investigation of archived tissue samples from 3 lions displaying nonsuppurative meningoencephalitis and vasculitis led to the detection of rustrela virus (RusV). We confirmed RusV antigen and RNA in cortical neurons, axons, astrocytes and Purkinje cells by reverse transcription quantitative PCR, immunohistochemistry, and in situ hybridization. [ABSTRACT FROM AUTHOR]