학술논문
Hemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS) following treatment with tisagenlecleucel.
Document Type
Case Study
Author
Martín‐Rojas, Reyes Maria; Gómez‐Centurión, Ignacio; Bailén, Rebeca; Bastos, Mariana; Diaz‐Crespo, Francisco; Carbonell, Diego; Correa‐Rocha, Rafael; Pion, Marjorie; Muñoz, Cristina; Sancho, Milagros; Gómez Fernández, Isabel; Oarbeascoa, Gillen; Pérez‐Corral, Ana; Martínez‐Laperche, Carolina; Anguita, Javier; Buño, Ismael; Menárguez, Javier; Díez‐Martín, Jose Luis; Kwon, Mi
Source
Subject
*MACROPHAGE activation syndrome
*HEMOPHAGOCYTIC lymphohistiocytosis
*CYTOKINE release syndrome
*CHIMERIC antigen receptors
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Language
ISSN
2050-0904
Abstract
Chimeric antigen receptor (CAR) T cell–related HLH/MAS is an unusual manifestation of severe cytokine release syndrome (CRS) with poor prognosis and a challenging diagnosis. The establishment of specific diagnosis criteria is essential, and the combination of several techniques for CAR T‐cell follow‐up, allows a more precise management of this complication. [ABSTRACT FROM AUTHOR]