학술논문

Global analysis of the yeast knockout phenome.
Document Type
Article
Source
Science Advances. 5/26/2023, Vol. 9 Issue 21, p1-17. 17p.
Subject
Language
ISSN
2375-2548
Abstract
The article provides information on the Yeast Phenome, a data library that aggregates and analyzes over 14,500 yeast knockout screens, resulting in the most comprehensive phenotypic description of any organism. The analysis of this dataset reveals new insights, including the identification of two unknown genes and the discovery of an exponential relationship between phenotypic similarity and intergenic distance, suggesting optimized gene positions in yeast and human genomes for function.