학술논문
First‑in‑Class Oral Semaglutide: Overcoming Barriers of Incretinisation in the Indian Context.
Document Type
Article
Author
Source
Subject
*TYPE 2 diabetes
*GLUCAGON-like peptide-1 agonists
*SEMAGLUTIDE
*GLYCEMIC control
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*
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Language
ISSN
2230-8210
Abstract
Despite the availability of multiple therapeutic options and strategies, patients with type 2 diabetes mellitus (T2DM) the world over have inadequate glycaemic control and India is no exception. Patients with T2DM in India have benefitted from glucagon‑like peptide‑1 analogues similar to that of patients from other parts of the world. However, subcutaneous treatment with glucagon‑like peptide‑1 receptor agonists (GLP‑1 RAs) is limited by their injectable mode of administration. The present review highlights barriers to incretinisation with GLP‑1RAs and the role of first‑in‑class oral semaglutide in the Indian context and provides guidance to physicians on its initiation and uses. [ABSTRACT FROM AUTHOR]