학술논문

Impact of high-throughput screening in biomedical research.
Document Type
Review
Source
Nature Reviews Drug Discovery. Mar2011, Vol. 10 Issue 3, p188-195. 8p. 1 Diagram, 3 Charts, 2 Graphs.
Subject
*HIGH throughput screening (Drug development)
*MEDICAL research
*BIOLOGICAL research
*PHARMACEUTICAL industry
*DRUG therapy
*ANIMALS
*CHEMICAL laboratory equipment
*DRUG design
*CLINICAL drug trials
*DRUG development
*STANDARDS
Language
ISSN
1474-1776
Abstract
High-throughput screening (HTS) has been postulated in several quarters to be a contributory factor to the decline in productivity in the pharmaceutical industry. Moreover, it has been blamed for stifling the creativity that drug discovery demands. In this article, we aim to dispel these myths and present the case for the use of HTS as part of a proven scientific tool kit, the wider use of which is essential for the discovery of new chemotypes. [ABSTRACT FROM AUTHOR]