학술논문
Imatinib mesylate induced erythroderma: A rare case series.
Document Type
Case Study
Author
Source
Subject
*IMATINIB
*SEZARY syndrome
*PROTEIN-tyrosine kinase inhibitors
*TREATMENT of chronic myeloid leukemia
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Language
ISSN
0973-1482
Abstract
Imatinib is a tyrosine kinase inhibitor approved as a first line treatment for chronic myeloid leukemia and gastrointestinal stromal tumors. Usually the drug is well-tolerated with hematological adverse effects being most commonly seen. Dermatological side effects are seen in 9.5-69% of patients on imatinib; majority of which are minor and self-limiting. We, hereby, report a case series of erythroderma occurring secondary to imatinib in two patients with chronic myeloid leukemia. Both the patients improved upon the discontinuation of the drug. The literature review revealed only six probable cases of erythroderma due to imatinib. So, this case series is being reported for the rarity of this adverse effect of imatinib. [ABSTRACT FROM AUTHOR]