학술논문

Epigenetic dynamics during capacitation of naïve human pluripotent stem cells.
Document Type
Article
Source
Science Advances. 9/29/2023, Vol. 9 Issue 39, p1-20. 20p.
Subject
*PLURIPOTENT stem cells
*HUMAN stem cells
*EPIGENETICS
*EPIGENOMICS
*IMMUNOPRECIPITATION
*LIFE sciences
*GENE expression
*GENE enhancers
Language
ISSN
2375-2548
Abstract
The article focuses on characterizing the epigenetic dynamics of human pluripotent stem cells (PSCs) during their transition from a naive state to a primed state. It highlights the differences between capacitated and conventional human PSCs, showing that capacitated PSCs are more transcriptionally similar to the post implantation epiblast than conventional PSCs.