부산대학교 도서관

: PurposeTo evaluate the treatment of subfoveal choroidal neovascularization (CNV) using photodynamic therapy (PDT) with verteporfin (Visudyne; Novartis, Duluth, GA) in young adults.: DesignRetrospective noncomparative interventional case series.: ParticipantsNineteen eyes of 17 patients with classic, subfoveal CNV treated with PDT using verteporfin, excluding eyes with CNV secondary to age-related macular degeneration, angioid streaks, and myopia.: Main outcome measuresSnellen visual acuity before and after PDT.: ResultsNineteen eyes were followed an average of 12.8 months (range, 4–33 months) after PDT. Before treatment, visual acuity measured ≥20/40 in 0 eyes (0.0%), <20/40 to >20/200 in 11 eyes (57.9%), and ≤20/200 in 8 eyes (42.1%). After treatment, visual acuity measured ≥20/40 in four eyes (21.1%), <20/40 to >20/200 in eight eyes (42.1%), and ≤20/200 in seven eyes (36.8%). Six eyes (31.6%) underwent retreatment, with only two eyes retreated twice. Four eyes underwent eventual surgical removal of the CNV after PDT.: ConclusionsPhotodynamic therapy seems to be useful in stabilizing and improving visual acuity in young adults with subfoveal CNV secondary to idiopathic and inflammatory etiologies. [Copyright &y& Elsevier]